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Recombinant Human PPT1 Protein (His Tag)
SKU: PKSH032848-50
Recombinant Human PPT1 Protein (His Tag)
| SKU # | PKSH032848 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | PPT-1, PPT1, Palmitoyl-protein hydrolase 1, Palmitoyl-protein thioesterase 1 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Asp28-Gly306 |
| Accession | P50897 |
| Calculated Molecular Weight | 32.3 kDa |
| Observed Molecular Weight | 34-41 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5. |
| Reconstitution | Not Applicable |
Background
Palmitoyl-protein thioesterase 1(PPT-1 for short), also known as Palmitoyl-protein hydrolase 1, belongs to the palmitoyl-protein thioesterase family. It is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. This enzyme removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Defects in PPT1 are the cause of neuronal ceroid lipofuscinosis type 1.