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Recombinant Human PSG2 Protein (His Tag)
SKU: PKSH032924-50
Recombinant Human PSG2 Protein (His Tag)
| SKU # | PKSH032924 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | PSBG2, PSG2, Pregnancy specific beta-1-glycoprotein 2, Pregnancy-specific beta-1 glycoprotein E, pregnancy-specific beta-1-glycoprotein 2, pregnancy-specific beta-1-glycoprotein 7 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gln35-Thr335 |
| Accession | P11465 |
| Calculated Molecular Weight | 34.5 kDa |
| Observed Molecular Weight | 43 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Reconstitution | Not Applicable |
Background
PSG2 is a secreted protein that in humans is encoded by the PSG2 gene. It is a member of the human pregnancy-specific glycoproteins (PSGs) family. These proteins are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. PSG2 consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. It has an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain.