Total Price: $0.00
Contact Information
Recombinant Human PTCH1 protein (His tag)
SKU: PDEH100432-100
To better serve you, we would like to discuss your specific requirement.
Please Contact Us for a quote.
Recombinant Human PTCH1 protein (His tag)
| SKU # | PDEH100432 |
| Expression Host | E. coli |
Description
| Synonyms | Protein patched homolog 1;PTCH1;PTC;PTC1 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Glu 122-Asp 436 |
| Accession | Q13635 |
| Mol_Mass | 34.5 kDa |
| AP_Mol_Mass | 38 kDa |
| Tag | N-His |
| Bio_Activity | Not validated for activity |
Propertie
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.