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Recombinant Human RBP4 Protein– MSE Supplies LLC

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Recombinant Human RBP4 Protein

SKU: PKSH033427-50

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Recombinant Human RBP4 Protein

 

SKU # PKSH033427
Expression Host E.coli

 

 

Description

Synonyms PRBP, Plasma Retinol-Binding Protein, RBP, RBP4, RDCCAS, Retinol-Binding Protein 4
Species Human
Expression Host E.coli
Sequence Glu19-Leu201
Accession P02753
Calculated Molecular Weight 21.2 kDa
Observed Molecular Weight 20 kDa
Tag None
Bio-activity Not validated for activity
  

 

Properties

Purity > 90 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 50mM Tris-HCl, 10mM CaCl2, 150mM NaCl, pH 7.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.



Background

Retinol Binding Protein 4 (RBP4) is a member of the Lipocalin family and in the blood. RBP4 is the specific vector for retinol. RBP4 is expressed and secreted by adipose tissue; and is associated with insulin resistance. RBP4 delivers retinol from the liver stores to the peripheral tissues. In plasma; the RBP-retinol complex interacts with transthyretin to prevents its loss by filtration through the kidney glomeruli. Defects in RBP4 cause retinol-binding protein deficiency and can cause night vision problems.