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Recombinant Human RPLP1 protein (His,GST tag)
SKU: PDEH100338-100
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Recombinant Human RPLP1 protein (His,GST tag)
| SKU # | PDEH100338 |
| Expression Host | E. coli |
Description
| Synonyms | 60S acidic ribosomal protein P1;RPLP1;Large ribosomal subunit protein P1;RRP1 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Met 1-Asp 114 |
| Accession | P05386 |
| Mol_Mass | 37.4 kDa |
| AP_Mol_Mass | 58 kDa |
| Tag | N-GST & C-His |
| Bio_Activity | Not validated for activity |
Propertie
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
RPLP1 (ribosomal protein large P1) is part of the 60S ribosomal subunit and functions in regulating elongation translation factors, and its expression is regulated by the estrogen target gene, c-Myc. RPLP1 has two alternatively spliced transcript variants that encode different proteins, with variant 1 coding for a protein of ~12-kDa molecular weight and variant 2 coding for an ~8.4-kDa protein, and the variant 1-transcribed protein appears as the major isoform. RPLP1 is proposed to play a role in diseases associated with cell proliferation and cell survival.