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Recombinant Human S100A6 Protein (Baculovirus, His Tag)
SKU: PKSH031347-50
Recombinant Human S100A6 Protein (Baculovirus, His Tag)
| SKU # | PKSH031347 |
| Expression Host | Baculovirus-Insect Cells |
Description
| Synonyms | 2A9, 5B10, CABP, CACY, Calcyclin, Growth factor-inducible protein 2A9, MLN 4, PRA, Prolactin receptor-associated protein, Protein S100-A6, S100 calcium-binding protein A6, S100A6 |
| Species | Human |
| Expression Host | Baculovirus-Insect Cells |
| Sequence | Met 1-Gly 90 |
| Accession | NP_055439.1 |
| Calculated Molecular Weight | 12 kDa |
| Observed Molecular Weight | 12 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 96 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile 50mM Tris, 100mM NaCl, 0.5mM PMSF, 1mM TCEP, pH 8.0 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
S100 proteinis a family of low molecular weight protein found in vertebrates characterized by twoEF-hand calcium-binding motifs. There are at least 21 different S100 proteins; and the name is derived from the fact that the protein is100%soluble in ammonium sulfateat neutralpH. Most S100 proteins are disulfide-linked homodimer; and is normally present in cells derived from theneural crest; chondrocytes; macrophages; dendritic cells; etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation; transcription factors; the dynamics of cytoskeleton constituents; enzyme activities; cell growth and differentiation; and the inflammatory response. S100A6 (S100 calcium binding protein A6) is a member of the S100 family of proteins; and functions in prolactin secretion; and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma.