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Recombinant Human S100P/S100E Protein (His Tag)
SKU: PKSH033009-50
Recombinant Human S100P/S100E Protein (His Tag)
| SKU # | PKSH033009 |
| Expression Host | E.coli |
Description
| Synonyms | MIG9, Protein S100-E, Protein S100-P, S100 Calcium-Binding Protein P, S100E, S100P |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Lys95 |
| Accession | P25815 |
| Calculated Molecular Weight | 12.6 kDa |
| Observed Molecular Weight | 12 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 100mM Nacl, 20% Glycerol, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Protein S100-P (S100P) belongs to the S100 family of Calcium-Binding Proteins. S100P is 95 amino acids in length and it contains 2 EF-Hand Calcium-Binding Motifs. The EF-Hand Motif binds calcium; which likely alters molecular conformation. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and it is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. In addition to binding Ca; S100P also binds Zn and Mg; and may play a role in the etiology of prostate cancer.