Recombinant Human SAA4 Protein (GST Tag)
SKU: PKSH031155-100
Recombinant Human SAA4 Protein (GST Tag)
SKU # | PKSH031155 |
Expression Host | E.coli |
Description
Synonyms | C-SAA, CSAA, Constitutively Expressed Serum Amyloid A Protein, SAA4, Serum Amyloid A-4 Protein |
Species | Human |
Expression Host | E.coli |
Sequence | Glu19-Tyr130 |
Accession | P35542 |
Calculated Molecular Weight | 39.8 kDa |
Observed Molecular Weight | 36 kDa |
Tag | N-GST |
Bio-activity | Not validated for activity |
Properties
Purity | > 93 % as determined by reducing SDS-PAGE. |
Endotoxin | Please contact us for more information. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from sterile PBS, 0.5% Triton X-100, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background
SAA4 is a member of the SAA family.SAA proteins are family of apolipoproteins of high density lipoprotein (HDL). They can be separated into two distinct groups. First group (SAA1; SAA2; and SAA3) consists of acute phase reactant whose expression level increase in the blood in a response to trauma; infection; inflammation; and neoplasia. These acute phase SAAs associates with HDL during inflammation and remodel the HDL particle by displacing Apo-A1. The second distinct group consists of SAA4 and SAA5 which exist as the minor apolipoproteins on HDL; but this group of SAA constitutes more than 90% of all the SAA during homeostasis; and it is thought to play a role in the normal functioning of the HDL particle. SAA4 is a constitutively expressed protein which expressed only in humans and mice.It is connected almost completely with lipoproteins of the high density range. The physiological function of SAA4 is unknown; and its serum concentration has no association with those of other major apolipoproteins.