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Recombinant Human ST14/Matriptase protein (His tag)
SKU: PDEH100283-100
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Recombinant Human ST14/Matriptase protein (His tag)
| SKU # | PDEH100283 |
| Expression Host | E. coli |
Description
| Synonyms | Epithin;HAI;Membrane type serine protease 1;MTSP1;Prostamin;PRSS14;Serine protease 14;SNC19;ST14;TADG15;TMPRSS14 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Thr 571-Val 855 |
| Accession | Q9Y5Y6 |
| Mol_Mass | 31.2 kDa |
| AP_Mol_Mass | 35 kDa |
| Tag | N-His |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH). ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.