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Recombinant Human Transaldolase/TALDO1 Protein (His Tag)
SKU: PKSH033132-50
Recombinant Human Transaldolase/TALDO1 Protein (His Tag)
| SKU # | PKSH033132 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | TAL, TALDO, TALDO1, TALDOR, Transaldolase |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Met 1-Lys337 |
| Accession | P37837 |
| Calculated Molecular Weight | 38.6 kDa |
| Observed Molecular Weight | 38 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Transaldolase (TALDO1) belongs to the transaldolase family of Type 1 subfamily. TALDO1 is expressed selectively in oligodendrocytes of the brain. TALDO1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. TALDO1 deficiency results in telangiectases of the skin, hepatosplenomegaly and enlarged clitoris.