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Recombinant Human VSTM1 Protein (His Tag)
SKU: PKSH033222-50
Recombinant Human VSTM1 Protein (His Tag)
| SKU # | PKSH033222 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | SIRL-1, Signal inhibitory receptor on leukocytes-1, V-set and transmembrane domain-containing protein 1, VSTM1 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Tyr17-Thr135 |
| Accession | Q6UX27 |
| Calculated Molecular Weight | 14.6 kDa |
| Observed Molecular Weight | 25-35 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
V-set and transmembrane domain-containing protein 1 is a single-pass membrane protein. VSTM1 Contains 1 Ig-like V-type domain, in humans is encoded by the VSTM1 gene. It expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. It behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). Inhibitory immune receptor involved in the regulation of phagocytes.