Total Price: $0.00
Contact Information
Recombinant Human XPNPEP2 Protein (His Tag)
SKU: PKSH033349-50
Recombinant Human XPNPEP2 Protein (His Tag)
| SKU # | PKSH033349 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | Aminoacylproline Aminopeptidase, Membrane-Bound APP, Membrane-Bound AmP, Membrane-Bound Aminopeptidase P, X-Pro Aminopeptidase 2, XPNPEP2, Xaa-Pro Aminopeptidase 2, mAmP |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | His22-Ala650 |
| Accession | O43895 |
| Calculated Molecular Weight | 71.6 kDa |
| Observed Molecular Weight | 78 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Xaa-Pro aminopeptidase 2 (XPNPEP2) belongs to the peptidase M24B family of metalloproteases. Human XPNPEP2 is widely expressed in various tissues; such as kidney; lung; heart; placenta; liver; small intestine and colon. However; it doesn’t express in brain; skeletal muscle; pancreas; spleen; thymus; prostate; testis and ovary. XPNPEP2 is a Homotrimer which binds 2 manganese ions per subunit. The metalloprotease XPNPEP2 may play a role in the inflammatory process and other reactions produced in response to injury or infection and the metabolism of the vasodilator bradykinin.