Total Price: $104.95
Contact Information
Recombinant Mouse IL-2RG/CD132 Protein (His Tag)
SKU: PKSM041317-50
Recombinant Mouse IL-2RG/CD132 Protein (His Tag)
| SKU # | PKSM041317 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | IMD, IL2RG, CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1, Cytokine receptor common subunit gamma, gammaC, Interleukin-2 receptor subunit gamma, common &, gamma- chain-n, IL-2R&, gamma |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Ser25-Ala263 |
| Accession | Q3UPA9 |
| Calculated Molecular Weight | 29 kDa |
| Observed Molecular Weight | 45-75 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.5. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
The Interleukin-2 receptor gamma chain (IL-2 Rγ, CD132) of the high affinity functional mouse IL-2 receptor complex is a member the hematopoietin receptor family. It is expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. Common IL2 receptor-γ Chain is required for IL-2 receptor signaling. Besides IL-2, the Common IL2 receptor-γ chain has been shown to be a component of the functional receptor complexes for IL-4, IL-7, IL-9 and IL-15. It is a component of multiple cytokine receptors that are essential for lymphocyte development and function. Common IL2 receptor-γ Chain is also designated the common gamma chain.