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Recombinant Mouse IL2Ra/CD25 Protein (His Tag) Purity >95%– MSE Supplies LLC

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Recombinant Mouse IL2Ra/CD25 Protein (His Tag) Purity >95%

SKU: PKSM041319-50

  • $ 28195
  • Save $ 3383



Recombinant Mouse IL2Ra/CD25 Protein (His Tag) Purity >95%

 

SKU # PKSM041319
Expression Host HEK293 Cells

 

 

Description

Synonyms IDDM, alpha, CD25, CD25 antigen, IDDM10, IL-2 R alpha, IL-2 receptor subunit alpha, IL-2R subunit alpha, IL2-RA, IL-2-RA, interleukin 2 receptor, Interleukin-2 receptor subunit alpha, Ly-43, p55, TAC antigen, TCGFR, Il2r, Il2ra, Tac,  p55,  Ly-43,  IL-2R&, alpha
Species Mouse
Expression Host HEK293 Cells
Sequence Glu22-Lys236
Accession P01590
Calculated Molecular Weight 25.5 kDa
Observed Molecular Weight 40-60 kDa
Tag C-His
Bio-activity Not validated for activity
  

 

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.



Background

The interleukin 2 receptor alpha (IL2RA), also called CD25, is a type I transmembrane protein that presents on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. IL2RA is a member of cytokine receptors family that utilizes the common gamma chain subunit (γc). IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. IL2RA associates with IL2RB (CD122) to form a heterodimer that can act as a high-affinity receptor for IL-2.