Recombinant Mouse IL2Ra/CD25 Protein (His Tag) Purity >95%
SKU: PKSM041319-50
Recombinant Mouse IL2Ra/CD25 Protein (His Tag) Purity >95%
SKU # | PKSM041319 |
Expression Host | HEK293 Cells |
Description
Synonyms | IDDM, alpha, CD25, CD25 antigen, IDDM10, IL-2 R alpha, IL-2 receptor subunit alpha, IL-2R subunit alpha, IL2-RA, IL-2-RA, interleukin 2 receptor, Interleukin-2 receptor subunit alpha, Ly-43, p55, TAC antigen, TCGFR, Il2r, Il2ra, Tac, p55, Ly-43, IL-2R&, alpha |
Species | Mouse |
Expression Host | HEK293 Cells |
Sequence | Glu22-Lys236 |
Accession | P01590 |
Calculated Molecular Weight | 25.5 kDa |
Observed Molecular Weight | 40-60 kDa |
Tag | C-His |
Bio-activity | Not validated for activity |
Properties
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background
The interleukin 2 receptor alpha (IL2RA), also called CD25, is a type I transmembrane protein that presents on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. IL2RA is a member of cytokine receptors family that utilizes the common gamma chain subunit (γc). IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. IL2RA associates with IL2RB (CD122) to form a heterodimer that can act as a high-affinity receptor for IL-2.