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Recombinant Porcine IGHE Protein (His tag)
SKU: PDMP100001-100
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Recombinant Porcine IGHE Protein (His tag)
| SKU # | PDMP100001 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | IGHE, IgE heavy chain constant region |
| Species | Porcine |
| Expression Host | HEK293 Cells |
| Sequence | Ser1-Lys424 |
| Accession | K7ZJQ0 |
| Calculated Molecular Weight | 46.5 kDa |
| Observed Molecular Weight | 65 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
Background
IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies-and the life threatening respiratory distress of asthma and anaphylactic shock.