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Recombinant Rat C1Inh Protein (His tag)
SKU: PDMR100015-100
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Recombinant Rat C1Inh Protein (His tag)
| SKU # | PDMR100015 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | C1 Inh, C1 esterase inhibitor, C1-inhibiting factor, C1Inh, Plasma protease C1 inhibitor, Serpin G1, Serping1 |
| Species | Rat |
| Expression Host | HEK293 Cells |
| Sequence | Met1-Ala504 |
| Accession | Q6P734 |
| Calculated Molecular Weight | 55.3 kDa |
| Observed Molecular Weight | 65 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
Background
Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein