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Recombinant Rat KLK6 Protein (His Tag)
SKU: PDER100008-100
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Recombinant Rat KLK6 Protein (His Tag)
| SKU # | PDER100008 |
| Expression Host | E. coli |
Description
| Synonyms | Bssp, KLK 6, KLK6, KLK9, Kallikrein 6 precursor, Kallikrein related peptidase 6, Kallikrein-6, Kallikrein6, Klk29, Klk6, Klk7, MGC9355, MSP, Neurosin, PRSS 18, PRSS 9, PRSS18, PRSS9, Protease M, Protease serine 18, Protease serine 9, Serine prote, hK 6, hK6, mGK 1, mGK1 |
| Species | Rat |
| Expression Host | E.coli |
| Sequence | Ile25-Pro261 |
| Accession | P36374-1 |
| Calculated Molecular Weight | 26.3 kDa |
| Observed Molecular Weight | 28.62 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 80 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.