TRIM25 Polyclonal Antibody Store at -20°C
SKU: E-AB-13732-200
TRIM25 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13732 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human TRIM25 |
| Abbre | TRIM25 |
| Synonyms | E3 ubiquitin/ISG15 ligase TRIM25, EFP, Estrogen responsive finger protein, Estrogen-responsive finger protein, RING finger protein 147, RNF 147, RNF147, TRI25, TRIM 25, Trim25, Tripartite m, Tripartite motif containing 25, Tripartite motif containing protein 25 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Colocalized with DDX58 at cytoplasmic perinuclear bodies. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.