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Recombinant 2019-nCoV NP CTD domain V2 (C-6His)
SKU: PKSV030279-1
Recombinant 2019-nCoV NP CTD domain V2 (C-6His)
| SKU # | PKSV030279 |
| Expression Host | E.coli |
Description
| Synonyms | 2019-nCoVcoronavirusNPProtein;2019-nCoVnpProtein;2019-nCoVnovelcoronavirusNucleoprotein Protein |
| Species | SARS-CoV-2 |
| Expression_host | E.coli |
| Sequence | Thr247-Pro364 |
| Accession | QHD43423.2 |
| Mol_Mass | 17.1 kDa |
| AP_Mol_Mass | 17 kDa |
| Tag | N-His |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μM filtered solution of 50mM PB, 150mM NaCl, 1mM EDTA, pH 7.4 |
| Reconstitution | Not Applicable |
Background
Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may beinvolved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packagesthe positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role duringvirion assembly through its interactions with the viral genome and membrane protein M. Plays an important rolein enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of theconservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as adiagnostic tool.