Total Price: $0.00
Contact Information
Recombinant chiken IGF1/IGF‑I/IGF-1 Protein (His tag)
SKU: PDEO100008-100
To better serve you, we would like to discuss your specific requirement.
Please Contact Us for a quote.
Recombinant chiken IGF1/IGF‑I/IGF-1 Protein (His tag)
| SKU # | PDEO100008 |
| Expression Host | E. coli |
Description
| Synonyms | interleukin-2;IL2;IL 2;IL-2;IL2;Interleukin 2 |
| Species | Chicken |
| Expression_host | E.coli |
| Sequence | Ala 23-Lys 143 |
| Accession | O73883 |
| Mol_Mass | 13.2 kDa |
| AP_Mol_Mass | 14 kDa |
| Tag | C-His |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Insulin-like growth factor I (IGF-I or IGF-1), also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally . IGF-I regulates glucose and fatty acid metabolism, steroid hormone activity, and cartilage and bone metabolism . It plays an important role in muscle regeneration and tumor progression . IGF-I/IGF-1 binds IGF-I R, IGF-II R, and the insulin receptor, although its effects are mediated primarily by IGF-I R . The IGF-I protein associates with IGF binding proteins thereby increasing its plasma half?life and modulating its interactions with receptors.