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Recombinant Green Monkey Calcitonin/CT Protein (His tag)
SKU: PDMC100001-100
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Recombinant Green Monkey Calcitonin/CT Protein (His tag)
| SKU # | PDMC100001 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CALCA, Calcitonin |
| Species | Green monkey |
| Expression Host | HEK293 Cells |
| Sequence | Ala26-Asn140 |
| Accession | A0A0D9QXH0 |
| Calculated Molecular Weight | 12.5 kDa |
| Observed Molecular Weight | 15 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Calcitonin(CT) is a protein hormones consist of 115aa with a disulfide bond. Calcitonin (CT) is most effectively produced by the parafollicular cells of the thyroid gland. It acts through the calcitonin receptor (CTR), a seven-transmembrane class II G-protein-coupled receptor linked to multiple signal transduction pathways with its main secretagogues being calcium and gastrin. Calcitonin regulates blood calcium levels and possesses certain clinically useful anti-fracture properties.