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Recombinant HIV p24 protein (C-6His)
SKU: PKSV030277-1
Recombinant HIV p24 protein (C-6His)
| SKU # | PKSV030277 |
| Expression Host | E.coli |
Description
| Synonyms | Capsid protein p24;Human immunodeficiency virus 1;Human immunodeficiency virus type 1 p24 |
| Species | HIV |
| Expression_host | E.coli |
| Sequence | Met142-Gly355 |
| Accession | P12493 |
| Mol_Mass | 24.6 kDa |
| AP_Mol_Mass | 25 kDa |
| Tag | C-His |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 5% Trehalose, 5% Mannitol,0.01% Tween 80, 1mM EDTA, pH 9.0. |
| Reconstitution | Not Applicable |
Background
The HIV1 p24 protein performs highly complex orchestrated tasks during the assembly,budding maturation and infection stages of the viral replication cycle. During viral assembly,the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag p24, the major capsid protein of the HIV-1 virion, has been used in clinical trials as one of the components of the HIV-1 vaccine because of the high degree of sequence conservation between different isolates. Recombinant HIV1-p24 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography.