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Recombinant Human AIMP2 protein (his tag)
SKU: PDEH100437-100
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Recombinant Human AIMP2 protein (his tag)
| SKU # | PDEH100437 |
| Expression Host | E. coli |
Description
| Synonyms | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2;AIMP2;Multisynthase complex auxiliary component p38;Protein JTV-1 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Met 1-Lys 320 |
| Accession | Q13155 |
| Mol_Mass | 35.1 kDa |
| AP_Mol_Mass | 30 kDa |
| Tag | N-His |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.