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Recombinant Human AKT2/PKB Beta Protein (His & GST Tag)
SKU: PKSH030382-50
Recombinant Human AKT2/PKB Beta Protein (His & GST Tag)
| SKU # | PKSH030382 |
| Expression Host | Baculovirus-Insect Cells |
Description
| Synonyms | HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA |
| Species | Human |
| Expression Host | Baculovirus-Insect Cells |
| Sequence | Met 1-Glu481 |
| Accession | NP_001617.1 |
| Calculated Molecular Weight | 83.6 kDa |
| Tag | N-His-GST |
| Bio-activity | Not validated for activity |
| Bio-activity | The specific activity was determined to be 17.4 nmol/min/mg using Poly(Glu, Tyr)4:1 peptide as substrate. |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 10 % glycerol,pH 7.4 |
| Reconstitution | Not Applicable |
Background
AKT2 (AKT Serine/Threonine Kinase 2) is a Protein Coding gene. Diseases associated with AKT2 include Hypoinsulinemic Hypoglycemia With Hemihypertrophy and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Constitutive Signaling by AKT1 E17K in Cancer and RANK Signaling in Osteoclasts. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AKT1.