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Recombinant Human Alpha-Parvin/PARVA Protein (His Tag)
SKU: PKSH033252-50
Recombinant Human Alpha-Parvin/PARVA Protein (His Tag)
| SKU # | PKSH033252 |
| Expression Host | E.coli |
Description
| Synonyms | Actopaxin, Alpha-Parvin, CH-ILKBP, Calponin-Like Integrin-Linked Kinase-Binding Protein, MXRA2, Matrix-Remodeling-Associated Protein 2, PARVA |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Glu372 |
| Accession | Q9NVD7 |
| Calculated Molecular Weight | 43.2 kDa |
| Observed Molecular Weight | 50-62 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 85 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 50mM Tris, 150mM NaCl, 40% Glycerol, pH 7.4. |
| Reconstitution | Not Applicable |
Background
Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis.