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Recombinant Human AZGP1 protein (His tag)
SKU: PDEH100173-100
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Recombinant Human AZGP1 protein (His tag)
| SKU # | PDEH100173 |
| Expression Host | E. coli |
Description
| Synonyms | Zinc-Alpha-2-Glycoprotein;Zn-Alpha-2-GP;Zn-Alpha-2-Glycoprotein;AZGP1;ZAG;ZNGP1 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Asn 148-Ser 298 |
| Accession | P25311 |
| Mol_Mass | 16.5 kDa |
| AP_Mol_Mass | 22 kDa |
| Tag | N-His |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Zinc-α-2-Glycoprotein (AZGP1) can be found in blood plasma; seminal plasma; urine; sweat; saliva; liver; and epithelial cells of various human glands. AZGP1 has been proposed in the regulation of body weight; and the melanin production by normal and malignant melanocytes. AZGP1 stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. AZGP1 has been reported to stimulate lipid breakdown and may have an important role in lipid homeostasis. Mature human AZGP1 consists of one MHC class I antigen region and a C2-type Ig-like domain. AZGP1 has two alternate splice forms; one shows a 66 amino acids substitution for the C-terminal 30 amino acids; the other one shows a nine Lys substitution for amino acid 151-298.