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Recombinant Human B4GALT4 Protein (His Tag)
SKU: PKSH033259-50
Recombinant Human B4GALT4 Protein (His Tag)
| SKU # | PKSH033259 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | 4-GalTase 4, 4-Galactosyltransferase 4, B4GALT4, Beta-1, Beta4Gal-T4, UDP-Gal:Beta-GlcNAc Beta-1, UDP-Galactose:Beta-N-Acetylglucosamine Beta-1, b4Gal-T4 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gln39-Ala344 |
| Accession | O60513 |
| Calculated Molecular Weight | 36.8 kDa |
| Observed Molecular Weight | 34-43 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5. |
| Reconstitution | Not Applicable |
Background
β-1,4-galactosyltransferase 4 (B4GALT4) is a single-pass type II membrane protein that belongs to the Glycosyltransferase 7 family. B4GALT4 consist of the following 2 domains: N-Acetyllactosamine Synthase and β-N-Acetylglucosaminyl-Glycolipid β-1,4-Galactosyltransferase. B4GALT4 is highly expressed in the heart, placenta, kidney, and pancreas; it is lowly expressed in the brain, colon, lung, muscle, ovary, testis, and uterus. B4GALT4 function is responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.