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Recombinant Human B7-H5/Gi24/VSIR Protein (His Tag)
SKU: PDMH100021-100
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Recombinant Human B7-H5/Gi24/VSIR Protein (His Tag)
| SKU # | PDMH100021 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | C10orf54, Platelet receptor Gi24, SISP1, Sisp-1, Stress-induced secreted protein-1 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Phe33-Ala194(Asp187Glu) |
| Accession | Q9H7M9 |
| Calculated Molecular Weight | 19.2 kDa |
| Observed Molecular Weight | 30-50 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
platelet receptor Gi24 is a single-pass type I membrane protein; and located at the cell surface. The protein can be cleaved by MMP14; and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling pathway. It also regulates the CD4-pasitive; alpha-beta T cell proliferation; and T cell cytokine production negatively. However; the protein can regulate stem cell differentiation positively.