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Recombinant Human BTN3A3 Protein (His Tag)
SKU: PDMH100018-100
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Recombinant Human BTN3A3 Protein (His Tag)
| SKU # | PDMH100018 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | BTF3, BTN3.3, BTN3A3, Butyrophilin subfamily 3 member A3 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gln30-Trp248 |
| Accession | O00478-1 |
| Calculated Molecular Weight | 24.6 kDa |
| Observed Molecular Weight | 30 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Human BTN3A3; also known as butyrophilin subfamily 3 member A3 and BTF3; is a Single-pass type I membrane protein which belongs to the immunoglobulin superfamily and BTN/MOG family. The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin domains and an intracellular B30.2 (PRYSPRY) domain. It can be detected in peripheral blood mononuclear cells; T-cells l; spleen and lymphocytes. BTN3A3 plays a role in T-cell responses in the adaptive immune response.