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Recombinant Human CALCB Protein (Fc Tag)
SKU: PKSH033301-50
Recombinant Human CALCB Protein (Fc Tag)
| SKU # | PKSH033301 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | Beta-type CGRP, CALC2, CALCB, Calcitonin gene-related peptide 2, Calcitonin gene-related peptide II |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Ala26-Phe118 |
| Accession | P10092 |
| Calculated Molecular Weight | 37 kDa |
| Observed Molecular Weight | 38-42 kDa |
| Tag | C-Fc |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
CALCB is a member of the calcitonin family. CALCB is produced in both peripheral and central neurons. It is a potent peptide vasodilator and can function in the transmission of pain. In the spinal cord; the function and expression of CGRP may differ depending on the location of synthesis. CALCB is derived mainly from the cell bodies of motor neurons when synthesized in the ventral horn of the spinal cord and may contribute to the regeneration of nervous tissue after injury.