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Recombinant Human Calmodulin 2/CALM2 Protein (His Tag)
SKU: PKSH030840-100
Recombinant Human Calmodulin 2/CALM2 Protein (His Tag)
| SKU # | PKSH030840 |
| Expression Host | E.coli |
Description
| Synonyms | CAMII, LQT15, PHKD, PHKD2, caM |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Lys149 |
| Accession | P0DP24 |
| Calculated Molecular Weight | 18.7 kDa |
| Observed Molecular Weight | 19-22 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 85 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Calmodulin 2, also known as CALM2, is a calmodulin. Calmodulin 2 mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). It is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Calmodulin 2 gene may be a genetic determinant of hip osteoarthritis (OA). OA is a degenerative disease characterized by gradual loss of articular cartilage and is a leading cause of disability in elderly populations. CALM2 was most abundantly expressed in articular chondrocytes and OA cartilage.