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Recombinant Human Carbonic Anhydrase 7/CA7 Protein (His Tag)(Active)
SKU: PKSH030890-100
Recombinant Human Carbonic Anhydrase 7/CA7 Protein (His Tag)(Active)
| SKU # | PKSH030890 |
| Expression Host | E.coli |
Description
| Synonyms | CA-VII, CA7, CAVII, Carbonate Dehydratase VII, Carbonic Anhydrase 7, Carbonic Anhydrase VII |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Ala 264 |
| Accession | P43166 |
| Calculated Molecular Weight | 31.0 kDa |
| Observed Molecular Weight | 33 kDa |
| Tag | C-His |
| Bio-activity | Measured by its esterase activity. The activity is > 20 pmoles/min/μg. |
Properties
| Purity | > 96 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Carbonic anhydrase 7; also known as carbonate dehydratase VII; carbonic anhydrase VII; CA-VII and CA7; is a cytoplasm protein which belongs to thealpha-carbonic anhydrase family. Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes; including respiration; calcification; acid-base balance; bone resorption; and the formation of aqueous humor; cerebrospinal fluid; saliva; and gastric acid. Carbonic anhydrases show extensive diversity in tissue distribution and in their subcellular localization. CA7 / CA-VII is predominantly expressed in the salivary glands. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms.