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Recombinant Human CD3D&CD3E Heterodimer (C-6His)
SKU: PKSH033922-50
Recombinant Human CD3D&CD3E Heterodimer (C-6His)
| SKU # | PKSH033922 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CD3 delta & CD3 epsilon, CD3 delta / epsilon, CD3E & CD3D |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Phe22-Ala105&Asp23-Asp126 |
| Accession | P04234&P07766 |
| Calculated Molecular Weight | 10.6&12.8 kDa |
| Observed Molecular Weight | 16-30 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
T-cell surface glycoprotein CD3D & CD3E, also known as CD3 delta & CD3 epsilon chain, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.