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Recombinant Human CD7/GP40 Protein (His Tag)
SKU: PKSH032223-50
Recombinant Human CD7/GP40 Protein (His Tag)
| SKU # | PKSH032223 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CD7, GP40, T-Cell Antigen CD7, T-Cell Leukemia Antigen, T-Cell Surface Antigen Leu-9, TP41 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Ala26-Pro180 |
| Accession | P09564 |
| Calculated Molecular Weight | 17.5 kDa |
| Observed Molecular Weight | 32 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
T-Cell Antigen CD7 is a single-pass type I membrane protein that that belongs to the the immunoglobulin superfamily. Human CD7 is synthesized as a 240 amino acid precursor that contains a 25 amino acid signal sequence and a 215 amino acid mature chain with a Ig-like (immunoglobulin-like) domain. CD7 is normally expressed on all T-lymphocytes; NK-cells; pre-B lymphocytes and pleuripotent hematopoietic stem cells. CD7 plays an essential role in T-cell interactions; T-cell/B-cell interaction during early lymphoid development; T- and NK-cell activation and cytokine production. CD7 has been shown to interact with PIK3R1and SECTM1. However; the function of the CD7 protein in the immune system is still largely unknown.