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Recombinant Human CEACAM7/CGM2 Protein (His Tag)
SKU: PKSH032238-50
Recombinant Human CEACAM7/CGM2 Protein (His Tag)
| SKU # | PKSH032238 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CEACAM7, CGM2, Carcinoembryonic Antigen CGM2, Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Thr36-Phe142 |
| Accession | AAI21133.1 |
| Calculated Molecular Weight | 13.1 kDa |
| Observed Molecular Weight | 20-30 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) is a member of the immunoglobulin superfamily A and CEA family. CEACAM7 localizes to the cell membrane and contains one Ig-like C2-type domain and one Ig-like V-type domain. The expression of CEACAM7 is significantly decreased in rectal cancer. Differences in CEACAM7 expression levels between long-term survivors and those with recurrent disease introduce a potential tumor marker to define a subset of patients who benefit most from adjuvant therapy.