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Recombinant Human CLEC4D/CLECSF8 Protein (His Tag)
SKU: PKSH031110-100
Recombinant Human CLEC4D/CLECSF8 Protein (His Tag)
| SKU # | PKSH031110 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CLEC-6, CLEC6, CLECSF8, MCL, MPCL |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gly 52-Asn 215 |
| Accession | NP_525126.2 |
| Calculated Molecular Weight | 21.2 kDa |
| Observed Molecular Weight | 21-27 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 92 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
C-type lectin (CLEC) family is a type of carbohydrate-binding protein domain named lectin. C-type lectins are the most diverse and prevalent lectin family in immunity with its requirement for calcium for binding. Proteins including a C-type lectin domain have diverse range of functions including cell-cell adhesion, immune response to pathogens and apoptosis. There are at least 14 types of C-type lectins: typeⅠto typeⅩⅣ. CLEC4D(CLECSF8) is a typeⅡ membrane glycoprotein belonging to the C-type lectin family, with restricted expression in the monocyte/macrophage lineage. It plays important roles in the function of macrophages.