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Recombinant Human CLIC4 Protein (His Tag)– MSE Supplies LLC

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Recombinant Human CLIC4 Protein (His Tag)

SKU: PKSH033334-50

  • £44400
  • Save £4900



Recombinant Human CLIC4 Protein (His Tag)

 

SKU # PKSH033334
Expression Host E.coli

 

 

Description

Synonyms CLIC4L, H1, MTCLIC, huH1, p64H1
Species Human
Expression Host E.coli
Sequence Met 1-Lys253
Accession Q9Y696
Calculated Molecular Weight 30.9 kDa
Observed Molecular Weight 32 kDa
Tag N-His
Bio-activity Not validated for activity
  

 

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.0.
Reconstitution Not Applicable



Background

Chloride Intracellular Channel Protein 4 (CLIC4) is a 253 amino acid single-pass membrane protein that localizes to both the nucleus and the cytoplasm and contains one GST C-terminal domain. CLIC4 is expressed in various tissues and exhibits an intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells). CLIC4 acts as a monomer which is able to form selective ion channels in target proteins; thus facilitating the transport of chloride and other ions. CLIC4 is believed to have a role in apoptosis and is able to translocate to the nucleus under stress conditions. CLIC4 has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis.