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Recombinant Human CRELD1 Protein (His Tag)– MSE Supplies LLC

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Recombinant Human CRELD1 Protein (His Tag)

SKU: PKSH030636-100

  • £51900
  • Save £5800



Recombinant Human CRELD1 Protein (His Tag)

 

SKU # PKSH030636
Expression Host HEK293 Cells

 

Description

Synonyms AVSD2, CIRRIN
Species Human
Expression Host HEK293 Cells
Sequence Met 1-Glu362
Accession NP_001070883.1
Calculated Molecular Weight 37.4 kDa
Observed Molecular Weight 51 kDa
Tag C-His
Bio-activity Not validated for activity
  

 

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, pH 7.4
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.


Background

CRELD1 is a transmembrane glycoprotein. Epidermal growth factor(EGF)&shy;like domain exists in CRELD1. EGF-like repeats are a class of cysteine-rich domains that mediate interactions between proteins of diverse function. EGF domains are found in proteins that are either completely secreted or have transmembrane regions that tether the protein to the cell surface. CRELD1 contains a 333 amino acid acid (aa) extracellular domain (ECD), two tandem transmembrane segments, and a second ECD of 15 aa. Defects in CRELD1 may cause susceptibility to atrioventricular septal defect type 2 which results in a persistent common atrioventricular canal.