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Recombinant Human DRP1 protein (His tag)
SKU: PDEH100411-100
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Recombinant Human DRP1 protein (His tag)
| SKU # | PDEH100411 |
| Expression Host | E. coli |
Description
| Synonyms | Dynamin-1-like protein;DNM1L;Dnm1p/Vps1p-like protein (DVLP);Dynamin family member proline-rich carboxyl-terminal domain less (Dymple);Dynamin-like protein |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Asn 448-Trp 736 |
| Accession | O00429 |
| Mol_Mass | 30.6 kDa |
| AP_Mol_Mass | 35 kDa |
| Tag | N-His |
| Bio_Activity | Not validated for activity |
Propertie
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into ring-like structures which wrap around the scission site to constict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Required for normal brain development. Facilitates developmentally-regulated apoptosis during neural tube development. Required for a normal rate of cytochrome c release and caspase activation during apoptosis. Also required for mitochondrial fission during mitosis. May be involved in vesicle transport.