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Recombinant Human Ephrin-A3/EFNA3 Protein (His Tag)
SKU: PKSH032390-50
Recombinant Human Ephrin-A3/EFNA3 Protein (His Tag)
| SKU # | PKSH032390 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | EFL-2, EFL2, EFNA3, EHK1 Ligand, EHK1-L, EPH-Related Receptor Tyrosine Kinase Ligand 3, EPLG3, Ephrin-A3, LERK-3, LERK3 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gln23-Ser211 |
| Accession | P52797 |
| Calculated Molecular Weight | 22.3 kDa |
| Observed Molecular Weight | 36 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. Ephrin-A3 has a GPI anchor following the extracellular sequence and a signal sequence of 22 amino acids. Ephrin-A3 can bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8 and EphB1. Futhermore, it is associated with tumor growth and metastasis.