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Recombinant Human ERP72/PDIA4 Protein (aa 21-645, His Tag)
SKU: PKSH032956-50
Recombinant Human ERP72/PDIA4 Protein (aa 21-645, His Tag)
| SKU # | PKSH032956 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | ER Protein 70, ER Protein 72, ERP70, ERP72, ERp-72, ERp70, ERp72, Endoplasmic Reticulum Resident Protein 70, Endoplasmic Reticulum Resident Protein 72, PDIA4, Protein Disulfide-Isomerase A4 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Val21-Leu645 |
| Accession | P13667 |
| Calculated Molecular Weight | 71.7 kDa |
| Observed Molecular Weight | 75 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5. |
| Reconstitution | Not Applicable |
Background
Protein Disulfide-Isomerase A4 (PDIA4) is an endoplasmic reticulum luminal protein that belongs to the protein disulfide isomerase family. Human PDIA4 is synthesized as a 625 amino acid precursor that contains a 20 amino acid signal sequence; and a 625 amino acid mature chain; including three thioredoxin domains. PDIA4 catalyzes the rearrangement of -S-S- bonds in proteins and is thought to be a deoxycytidine kinase. In addition; PDIA4 serves as a proteases protein disulfide isomerase; phospholipase or an arrangement of these.