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Recombinant Human ETS1/EWSR2 Protein (His Tag)
SKU: PKSH032408-50
Recombinant Human ETS1/EWSR2 Protein (His Tag)
| SKU # | PKSH032408 |
| Expression Host | E.coli |
Description
| Synonyms | ETS1, ETS1 Protein, Isoform CRA_a, Protein C-ets-1, V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian), hCG_1732038 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Thr 272 |
| Accession | P14921-5 |
| Calculated Molecular Weight | 33.0 kDa |
| Observed Molecular Weight | 38 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, 1mM EDTA, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death Associated Protein 6.