Total Price: $0.00
Contact Information
Recombinant Human FCGR1A/CD64 Protein (His tag)
SKU: PDMH100112-100
Recombinant Human FCGR1A/CD64 Protein (His tag)
| SKU # | PDMH100112 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CD antigen CD64, Fc-gamma RI, Fc-gamma RIA, FcRI, FcgammaRIa, High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Met1-Pro288 |
| Accession | P12314 |
| Calculated Molecular Weight | 31.6 kDa |
| Observed Molecular Weight | 35 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
Background
CD64 (FcγRI), one of the Fc receptors for IgG, is a membrane glycoprotein that mediates endocytosis, phagocytosis, antibody-dependent cellular cytotoxicity, cytokine release, and superoxide production. CD64 is also structurally distinct, containing an extracellular Ig-interactive region of three Ig-like domains in contrast to the two domains of the low affinity receptors FcγRII and FcγRIII. It is normally expressed on the surfaces of monocytes and macrophages.