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Recombinant Human FGF-2/FGFb Protein (aa 134-288)(Active)– MSE Supplies LLC

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Recombinant Human FGF-2/FGFb Protein (aa 134-288)(Active)

SKU: PKSH032438-100

  • £18300
  • Save £2000



Recombinant Human FGF-2/FGFb Protein (aa 134-288)(Active)

 

SKU # PKSH032438
Expression Host E.coli

 

 

Description

Synonyms Basic fibroblast growth factor, Bfgf, FGF-2, FGF2, FGFB, Fibroblast growth factor 2, HBGF-2, Heparin-binding growth factor 2
Species Human
Expression Host E.coli
Sequence Ala144-Ser288
Accession P09038
Calculated Molecular Weight 18.1 kDa
Observed Molecular Weight 17 kDa
Tag None
Bio-activity Measure by its ability to induce 3T3 cells proliferation. The ED50 for this effect is <1 ng/mL. The specific activity of recombinant human FGF-2 is approximately >5 x 105 IU/mg.
  

 

Properties

Purity > 98 % as determined by reducing SDS-PAGE.
Endotoxin < 0.1 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS with 0.01% sarkosyl,pH 8.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.



Background

Fibroblast growth factor 2(FGF2) is a secreted protein and belongs to the heparin-binding growth factors family. FGF2 is produced by epithelial; tumor and other cell types. It involved in developmental processes and regulates differentiation; proliferation; and migration; FGF2 is a critical factor for growing embryonic stem cells in culture without inducing differentiation. FGF2 has a high affinity for heparan sulfate and binding is a step in the FGF basic activation of FGFR tyrosine kinase.