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Recombinant Human FGF23 protein (SUMO,His tag)
SKU: PDEH100192-100
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Recombinant Human FGF23 protein (SUMO,His tag)
| SKU # | PDEH100192 |
| Expression Host | E. coli |
Description
| Synonyms | FGF-23;Fgf23;ADHR;FGF23;fibroblast growth factor 23;HPDR2;HYPF;phosphatonin;PHPTC |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Ala 24-Val 126 |
| Accession | Q9GZV9 |
| Mol_Mass | 31.2 kDa |
| AP_Mol_Mass | 32 kDa |
| Tag | N-SUMO-His |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).