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Recombinant Human GALNT2/GalNAc-T2 Protein (His Tag)
SKU: PKSH030561-50
Recombinant Human GALNT2/GalNAc-T2 Protein (His Tag)
| SKU # | PKSH030561 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | GalNAc-T2 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Lys52-Gln571 |
| Accession | NP_004472.1 |
| Calculated Molecular Weight | 61.6 kDa |
| Observed Molecular Weight | 57-65&46 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile 25 mM Tris, 150 mM NaCl, 0.05% Brij-35, pH 7.5 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
GALNT2, also known as GalNAc-T2, is a member of the GalNAc-transferases family. Members of this family transfer an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. GALNT2 may play a role in lipid metabolism. It catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GALNT2 has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b.