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Recombinant Human GLP1R Protein (Fc Tag)
SKU: PKSH033669-50
Recombinant Human GLP1R Protein (Fc Tag)
| SKU # | PKSH033669 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | GLP-1 receptor, GLP-1-R, Glucagon-like peptide 1 receptor |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Arg24-Tyr145 |
| Accession | P43220 |
| Calculated Molecular Weight | 41.2 kDa |
| Observed Molecular Weight | 50-75 kDa |
| Tag | C-Fc |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
GLP1R Belongs to the G-protein coupled receptor 2 family that is synthesized as a 172 amino acid (aa). GLP1R is expressed in pancreas, lung, heart, kidney, hypothalamus, and stomach. It may form homodimers and heterodimers with GIPR. GLP1R is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.