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Recombinant Human GPD1/GDP-C Protein (E.coli, His Tag)
SKU: PKSH030541-100
Recombinant Human GPD1/GDP-C Protein (E.coli, His Tag)
| SKU # | PKSH030541 |
| Expression Host | E.coli |
Description
| Synonyms | GPD-C, GPD1, GPDH-C, Glycerol-3-Phosphate Dehydrogenase [NAD(+)] Cytoplasmic, HTGTI |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Met349 |
| Accession | P21695 |
| Calculated Molecular Weight | 39.4 kDa |
| Observed Molecular Weight | 33-37 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile 50mM Tris, 10% glycerol, pH 8.0 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
GPD1; also known as glycerolphosphate dehydrogenase 1; is a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. GPD1 catalyzes the reversible redox conversion ofdihydroxyacetone phosphate (DHAP); thus plays a critical role in carbohydrate and lipid metabolism. It also reduces nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. Meanwhile; GPD1 and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in GPD1 gene are a cause of transient infantile hypertriglyceridemia.