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Recombinant Human GPD1/GDP-C Protein (Human Cells, His Tag)
SKU: PKSH032505-50
Recombinant Human GPD1/GDP-C Protein (Human Cells, His Tag)
| SKU # | PKSH032505 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | GPD-C, GPD1, GPDH-C, Glycerol-3-Phosphate Dehydrogenase [NAD(+)] Cytoplasmic, HTGTI |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Met 1-Met349 |
| Accession | P21695 |
| Calculated Molecular Weight | 38.6 kDa |
| Observed Molecular Weight | 32-48 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Glycerol-3-Phosphate Dehydrogenase [NAD(+)]; Cytoplasmic (GPDH-C) belongs to the NAD-Dependent Glycerol-3-Phosphate Dehydrogenase family. GPDH-C plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of Dihydroxyacetone Phosphate (DHAP) and reducing Nicotine Adenine Dinucleotide (NADH) to Glycerol-3-Phosphate (G3P) and NAD+. GPDH-C is inhibited by zinc ions and sulfate. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. GPDH-C is unlike Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH); they have different substrates.