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Recombinant Human HCLS1 Protein (His Tag)
SKU: PKSH032527-50
Recombinant Human HCLS1 Protein (His Tag)
| SKU # | PKSH032527 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | Hematopoietic cell-specific LYN substrate 1, Hematopoietic lineage cell-specific protein, LckBP1, p75 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Met 1-Glu486 |
| Accession | AAH16758.1 |
| Calculated Molecular Weight | 55.0 kDa |
| Observed Molecular Weight | 55-110 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Reconstitution | Not Applicable |
Background
Hematopoietic lineage cell-specific protein (HCLS1) is a protein that in humans is encoded by the HCLS1 gene. It is expressed only in tissues and cells of hematopoietic origin. It is substrate of the antigen receptor-coupled tyrosine kinase and plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. It may also be involved in the regulation of gene expression.